Study on the Phytochemical, Antioxidant and In Vitro Anticancer activity on root extract of Simarouba glauca DC

Plant made medicine plays main role in drug formulation and synthesis with moderate or no side effects. Simarouba glauca is exotic to India known for its phytomedicine property belonging the Simaroubaceae family prominent leaves arrangement called “Lakshmi taru” “Paradise tree”. The goal of this study was present preliminary phytochemicals, antioxidants, cytotoxicity mechanism S. root extracts terms apoptosis cell cycle. Phytochemical, qualitative, antioxidant assay analyses were performed standard protocol using HPTLC studies analysed a flow-cytometer. Phytochemical screening revealed presence saponins, flavonoids, steroids, triterpenoids. Furthermore, demonstrated potent activity could serve as lead source natural antioxidants. In concentration-dependent manner, anticancer against A549 line by stopping cells at S-phase. investigation reveals antiproliferative properties methanolic extract. Identification cytotoxic compounds their mode action require further in-depth research. outcome our offers compelling evidence that extract can be used an effective ethnomedicinal agent ability treat human disorders.